The Lord of Pain

an Assassin deals combat damage — 212 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain deals combat damage:

1. Layla Hassan — brings a card back
2. Ezio, Blade of Vengeance — draws you 1 card
3. Etrata, Deadly Fugitive — triggers
4. Jacob Frye — exiles a card from your graveyard

an Assassin attacks — 212 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain attacks:

1. The Revelations of Ezio — puts a counter on a permanent
2. Origin of the Hidden Ones — makes a token

an Assassin creature it grants types to — 219 cards in the game can cause this.

1. Reaper's Scythe — Reaper's Scythe gives The Lord of Pain an extra creature type

218 other cards cause it too. These are the ones with the most connections.

anything deals noncombat damage — 3,068 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain deals noncombat damage:

1. Quest for Pure Flame — puts a quest counter on itself
2. Fear of Burning Alive — deals that amount damage
3. Niv-Mizzet, Visionary — draws you that many cards
4. Chandra's Incinerator — deals that much damage
5. Chandra's Pyreling — gets +1/+0
6. Talon of Pain — puts a charge counter on itself
7. Asgardian Inspiration — returns itself from the graveyard
8. Thor, Guardian of Midgard — exiles a card from your library
9. Virtue of Courage // Embereth Blaze — exiles a card from your library

37 other cards care about it too. These are the ones with the most connections.

life is lost — 3,160 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain makes a player lose life:

1. Far Fortune, End Boss — raises your speed
2. Zahur, Glory's Past — raises your speed
3. Mendicant Core, Guidelight — raises your speed
4. Aether Syphon — raises your speed
5. Vnwxt, Verbose Host — raises your speed
6. Embalmed Ascendant — raises your speed
7. Slick Imitator — raises your speed
8. Oath of Lim-Dûl — sacrifices an enchantment
9. Marina Vendrell's Grimoire — triggers
10. Lich's Mastery — triggers

46 other cards care about it too. These are the ones with the most connections.

a Human enters the battlefield — 4,639 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain enters:

1. General Kudro of Drannith — hits a graveyard
2. Heronblade Elite — puts a +1/+1 counter on itself
3. Kyler, Sigardian Emissary — puts a +1/+1 counter on itself
4. Thalia's Lieutenant — puts a +1/+1 counter on itself
5. Champion of the Parish — puts a +1/+1 counter on itself
6. Captain of the Mists — untaps itself
7. Erkenbrand, Lord of Westfold — gives +1/+0
8. Beregond of the Guard — gives +1/+1
9. Théoden, King of Rohan — grants double strike
10. Lossarnach Captain — taps a creature an opponent controls

2 other cards care about it too. These are the ones with the most connections.

a creature attacks — 17,934 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain attacks:

1. Anthem of Rakdos — gives +2/+0
2. Adaptive Omnitool — searches a library
3. Kindred Discovery — draws you 1 card
4. Invasion of New Capenna // Holy Frazzle-Cannon — puts counters on a permanent
5. Saw — sacrifices a creature

186 other cards care about it too. These are the ones with the most connections.

anything attacks — 17,934 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain attacks:

1. Temmet, Naktamun's Will — draws you 1 card
2. Grim Javelineer — gives +1/+0
3. Invisible Woman — triggers
4. Caesar, Legion's Emperor — sacrifices a creature
5. Guide of Souls — triggers
6. Campsite Cuisine — sacrifices a Food
7. Gossip's Talent — triggers
8. Banon, the Returners' Leader — draws and discards
9. Toph, Earthbending Master — puts a counter on a permanent
10. Three Dog, Galaxy News DJ — sacrifices an Aura

111 other cards care about it too. These are the ones with the most connections.

a creature blocks — 17,934 cards in the game can cause this (The Lord of Pain is one).

1. Tide of War — When The Lord of Pain blocks, Tide of War sacrifices a creature

27 other cards care about it too. These are the ones with the most connections.

a creature enters the battlefield — 19,800 cards in the game can cause this (The Lord of Pain is one).

When The Lord of Pain enters:

1. Slash, Reptile Rampager — deals 2 damage
2. Gimli of the Glittering Caves — puts counters on a permanent
3. Ray Fillet, Wave Warrior — puts a counter on itself
4. Legolas Greenleaf — puts a counter on a permanent
5. The Neutrinos — gets +1/+0
6. Wingnut, Bat on the Belfry — grants flying, haste and menace
7. Aetherstorm Roc — puts a counter on a permanent you control
8. Raphael, Most Attitude — exiles a card from your library

304 other cards care about it too. These are the ones with the most connections.

anything enters the battlefield — 26,499 cards in the game can cause this (The Lord of Pain is one).

1. Prowl, Stoic Strategist // Prowl, Pursuit Vehicle — When The Lord of Pain enters, Prowl, Stoic Strategist // Prowl, Pursuit Vehicle puts a +1/+1 counter on itself

43 other cards care about it too. These are the ones with the most connections.