Emissary of Despair

a nontoken Spirit deals combat damage — 725 cards in the game can cause this (Emissary of Despair is one).

1. Millicent, Restless Revenant — When Emissary of Despair deals combat damage, Millicent, Restless Revenant makes a token

a nontoken Spirit enters the battlefield — 727 cards in the game can cause this (Emissary of Despair is one).

1. Baboon Spirit — When Emissary of Despair enters, Baboon Spirit makes a token

a Spirit enters the battlefield — 863 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair enters:

1. Mausoleum Wanderer — gets +1/+1
2. Drogskol Cavalry — gains you 2 life
3. Vanguard of the Restless — returns itself from the graveyard
4. Nebelgast Herald — taps a creature an opponent controls

life is lost — 3,160 cards in the game can cause this (Emissary of Despair is one).

When a permanent makes a player lose life thanks to Emissary of Despair:

1. Far Fortune, End Boss — raises your speed
2. Zahur, Glory's Past — raises your speed
3. Mendicant Core, Guidelight — raises your speed
4. Aether Syphon — raises your speed
5. Vnwxt, Verbose Host — raises your speed
6. Embalmed Ascendant — raises your speed
7. Slick Imitator — raises your speed
8. Nesting Bot — raises your speed
9. Howlsquad Heavy — raises your speed
10. Hour of Victory — raises your speed

46 other cards care about it too. These are the ones with the most connections.

anything attacks — 17,934 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair attacks:

1. Temmet, Naktamun's Will — draws you 1 card
2. Grim Javelineer — gives +1/+0
3. Invisible Woman — triggers
4. Caesar, Legion's Emperor — sacrifices a creature
5. Guide of Souls — triggers
6. Campsite Cuisine — sacrifices a Food
7. Gossip's Talent — triggers
8. Banon, the Returners' Leader — draws and discards
9. Toph, Earthbending Master — puts a counter on a permanent
10. Three Dog, Galaxy News DJ — sacrifices an Aura

111 other cards care about it too. These are the ones with the most connections.

a creature attacks — 17,934 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair attacks:

1. Adaptive Omnitool — searches a library
2. Anthem of Rakdos — gives +2/+0
3. Kindred Discovery — draws you 1 card
4. Invasion of New Capenna // Holy Frazzle-Cannon — puts counters on a permanent
5. Chorale of the Void — brings a card back
6. Anim Pakal, Thousandth Moon — puts a +1/+1 counter on itself
7. Saw — sacrifices a creature
8. Gisa's Favorite Shovel — makes an opponent sacrifice a creature
9. Ultima Weapon — kills a creature an opponent controls
10. Total War — kills a creature

180 other cards care about it too. These are the ones with the most connections.

a creature blocks — 17,934 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair blocks:

1. Mage Hunters' Onslaught — makes a player lose 1 life
2. Carnage Gladiator — makes a player lose 1 life
3. Barrow-Blade — strips abilities
4. Heat of Battle — deals 1 damage
5. Battle Strain — deals 1 damage
6. Favor of the Woods — gains you 3 life
7. Tide of War — sacrifices a creature
8. Dead-Iron Sledge — kills a creature
9. Dwindle — kills a creature
10. Shield of the Righteous — triggers

18 other cards care about it too. These are the ones with the most connections.

a nontoken creature attacks — 17,934 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair attacks:

1. Mardu Ascendancy — makes a token
2. Basri Ket — makes a token
3. Militia's Pride — makes a token

a creature deals combat damage — 17,934 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair deals combat damage:

1. Locutus of Borg — makes a token
2. Antagonist Incorporator — makes a token
3. Hive Mind Coprocessor — makes you lose life

194 other cards care about it too. These are the ones with the most connections.

a creature enters the battlefield — 19,800 cards in the game can cause this (Emissary of Despair is one).

When Emissary of Despair enters:

1. Slash, Reptile Rampager — deals 2 damage
2. Ray Fillet, Wave Warrior — puts a counter on itself
3. The Neutrinos — gets +1/+0
4. Wingnut, Bat on the Belfry — grants flying, haste and menace
5. Aetherstorm Roc — puts a counter on a permanent you control
6. Raphael, Most Attitude — exiles a card from your library

304 other cards care about it too. These are the ones with the most connections.

anything enters the battlefield — 26,499 cards in the game can cause this (Emissary of Despair is one).

1. Prowl, Stoic Strategist // Prowl, Pursuit Vehicle — When Emissary of Despair enters, Prowl, Stoic Strategist // Prowl, Pursuit Vehicle puts a +1/+1 counter on itself

39 other cards care about it too. These are the ones with the most connections.