Agent of the Iron Throne

an artifact is put into a graveyard from the battlefield — 428 cards in Agent of the Iron Throne's colors can cause this.

1. Straw Golem — When Straw Golem dies, Agent of the Iron Throne makes each opponent lose 1 life
2. Fire Navy Trebuchet — When a Construct dies thanks to Fire Navy Trebuchet, Agent of the Iron Throne makes each opponent lose 1 life
3. Heart-Shaped Herb — When a creature dies thanks to Heart-Shaped Herb, Agent of the Iron Throne makes each opponent lose 1 life
4. Ruthless Technomancer — When a creature dies thanks to Ruthless Technomancer, Agent of the Iron Throne makes each opponent lose 1 life
5. Trading Post — When you sacrifice a creature to Trading Post, Agent of the Iron Throne makes each opponent lose 1 life
6. Sivriss, Nightmare Speaker — When you sacrifice another creature or an artifact to Sivriss, Nightmare Speaker, Agent of the Iron Throne makes each opponent lose 1 life
7. Fain, the Broker — When you sacrifice a creature to Fain, the Broker, Agent of the Iron Throne makes each opponent lose 1 life
8. Scrounge for Eternity — When a creature dies thanks to Scrounge for Eternity, Agent of the Iron Throne makes each opponent lose 1 life
9. Extruder — When Extruder dies, Agent of the Iron Throne makes each opponent lose 1 life
10. Acidic Dagger — When a creature dies thanks to Acidic Dagger, Agent of the Iron Throne makes each opponent lose 1 life

418 other cards cause it too. These are the ones with the most connections.

life is lost — 1,256 cards in Agent of the Iron Throne's colors can cause this (Agent of the Iron Throne is one).

When a permanent makes a player lose life thanks to Agent of the Iron Throne:

1. Hour of Victory — raises your speed
2. Walking Sarcophagus — raises your speed
3. Gas Guzzler — raises your speed
4. Gastal Raider — raises your speed
5. Risen Necroregent — raises your speed
6. The Master of Lake-town — mills a card
7. Starting Column — raises your speed
8. Momentum Breaker — raises your speed
9. Racers' Scoreboard — raises your speed
10. Bloodthirsty Conqueror — gains you that much life

16 other cards care about it too. These are the ones with the most connections.

an enchantment is cast — 594 cards in Agent of the Iron Throne's colors can cause this (Agent of the Iron Throne is one).

When Agent of the Iron Throne is cast:

1. Blightcaster — shrinks a creature by -2/-2
2. Defiler of Flesh — gives +1/+1
3. The Fantasticar — turns something into a creature
4. Machine Man, Model X-51 — puts a +1/+1 counter on itself
5. Mai, Scornful Striker — makes a player lose 2 life
6. The Destined Black Mage — deals 1 damage
7. Shambling Cie'th — returns itself from the graveyard
8. Black Mage's Rod — deals 1 damage
9. Blood Funnel — sacrifices a creature
10. The Vision — triggers

3 other cards care about it too. These are the ones with the most connections.

an enchantment enters the battlefield — 597 cards in Agent of the Iron Throne's colors can cause this (Agent of the Iron Throne is one).

When Agent of the Iron Throne enters:

1. Doomwake Giant — shrinks a creature by -1/-1
2. Cacophony Unleashed — turns something into a creature
3. Grim Guardian — makes each opponent lose 1 life
4. Agent of Erebos — hits a graveyard
5. Dreadbringer Lampads — grants intimidate
6. Dashing Bloodsucker — gets +2/+0
7. Balemurk Leech — makes each opponent lose 1 life
8. Daxos's Torment — turns something into a creature
9. Brainstealer Dragon — makes a player lose life equal to its mana value
10. Thoughtrender Lamia — makes an opponent discard a card

18 other cards care about it too. These are the ones with the most connections.