Doctor Doom

a Villain enters the battlefield — 99 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When a Villain enters thanks to Doctor Doom:

1. Doom Reigns Supreme — makes each opponent lose 1 life
2. Crossbones, Malicious Mercenary — puts a +1/+1 counter on itself
3. Yellowjacket, Heartless Marauder — gets +1/+0
4. Swordsman, Sharp Scoundrel — triggers
5. Baron Strucker, HYDRA Overlord — draws and discards

life is lost — 1,256 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom makes a player lose life:

1. The Master of Lake-town — mills a card
2. Intermediate Chirography — puts a counter on a creature
3. Vilis, Broker of Blood — draws you that many cards
4. Vengeful Warchief — puts a +1/+1 counter on itself
5. Moonstone Harbinger — gives +1/+0
6. Oath of Lim-Dûl — sacrifices an enchantment
7. Lich's Mastery — triggers
8. Lich's Tomb — sacrifices a permanent
9. Gonti's Machinations — puts a counter on a permanent you control

17 other cards care about it too. These are the ones with the most connections.

a token is created — 726 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom makes a Robot or Villain token:

1. Idol of Oblivion — draws you 1 card
2. Mirkwood Bats — makes each opponent lose 1 life

a card is drawn — 789 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom makes a player draw a card:

1. Starving Revenant — makes each opponent lose 1 life
2. Diviner's Wand — gets +1/+1
3. Psychosis Crawler — makes each opponent lose 1 life
4. Sheoldred, the Apocalypse — gains you 2 life
5. Moonring Mirror — exiles a card from your library

10 other cards care about it too. These are the ones with the most connections.

an artifact enters the battlefield — 2,613 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When a Robot or Villain enters thanks to Doctor Doom:

1. Underhanded Designs — makes each opponent lose 1 life
2. Pactdoll Terror — makes each opponent lose 1 life
3. Arcbound Crusher — puts a +1/+1 counter on itself
4. Arcbound Condor — shrinks a creature by -1/-1
5. Glaze Fiend — gets +2/+2
6. Battered Golem — untaps itself
7. Skorpekh Destroyer — grants first strike
8. Grinding Station — untaps itself
9. Ovalchase Daredevil — returns itself from the graveyard
10. Vermiculos — gets +4/+4

6 other cards care about it too. These are the ones with the most connections.

a creature attacks — 3,478 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom attacks:

1. Adaptive Omnitool — searches a library
2. Chorale of the Void — brings a card back
3. Staff of Titania — makes a token
4. Inquisitorial Rosette — makes a token
5. Wand of Orcus — grants deathtouch
6. Andúril, Flame of the West — makes 2 tokens
7. Saw — sacrifices a creature
8. Gisa's Favorite Shovel — makes an opponent sacrifice a creature
9. Ultima Weapon — kills a creature an opponent controls
10. Throwing Knife — sacrifices itself

53 other cards care about it too. These are the ones with the most connections.

anything attacks — 3,478 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom attacks:

1. Grim Javelineer — gives +1/+0
2. ED-E, Lonesome Eyebot — puts a quest counter on itself
3. Fire Navy Trebuchet — makes a token
4. Stensian Sanguinist // Exsanguinate — grants deathtouch
5. Rev, Tithe Extractor — grants deathtouch
6. Boggart Prankster — gives +1/+0
7. Within Range — makes each opponent lose life
8. Curse of Disturbance — makes a token
9. Dawnsire, Sunstar Dreadnought — deals 100 damage
10. Twins of Discord — triggers

9 other cards care about it too. These are the ones with the most connections.

a creature blocks — 3,478 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom blocks:

1. Mage Hunters' Onslaught — makes a player lose 1 life
2. Barrow-Blade — strips abilities
3. Dead-Iron Sledge — kills a creature

3 other cards care about it too. These are the ones with the most connections.

a creature deals combat damage — 3,478 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

1. Hive Mind Coprocessor — When Doctor Doom deals combat damage, Hive Mind Coprocessor makes you lose life

63 other cards care about it too. These are the ones with the most connections.

a creature is cast — 3,493 cards in Doctor Doom's colors can cause this (Doctor Doom is one).

When Doctor Doom is cast:

1. Endrek Sahr, Master Breeder — makes that spell's mana value tokens
2. Oketra's Monument — makes a token
3. Skittering Horror — sacrifices itself
4. Skittering Skirge — sacrifices itself
5. Skittering Monstrosity — sacrifices itself

13 other cards care about it too. These are the ones with the most connections.