Chains of Mephistopheles

a card is milled — 772 cards in the game can cause this (Chains of Mephistopheles is one).

1. Lo and Li, Royal Advisors — When Chains of Mephistopheles makes a player mill a card, Lo and Li, Royal Advisors puts a counter on an Advisor

a card is discarded — 2,042 cards in the game can cause this (Chains of Mephistopheles is one).

When Chains of Mephistopheles makes a player discard a card:

1. Ivora, Insatiable Heir — puts a +1/+1 counter on itself
2. Cool but Rude — deals 2 damage
3. Containment Construct — brings a card back
4. Moonstone, Harsh Mistress — brings a card back
5. Sangromancer — gains you 3 life
6. Nath of the Gilt-Leaf — makes a token
7. Inti, Seneschal of the Sun — exiles a card from your library
8. Pitchstone Wall — sacrifices itself
9. Currency Converter — exiles it
10. Hostile Investigator — triggers

51 other cards care about it too. These are the ones with the most connections.

an enchantment is cast — 3,673 cards in the game can cause this (Chains of Mephistopheles is one).

When Chains of Mephistopheles is cast:

1. Hallowed Haunting — makes a token
2. Daxos the Returned — puts a counter on a permanent
3. Tatsunari, Toad Rider — makes a token
4. Sythis, Harvest's Hand — gains you 1 life
5. Sigil of the Empty Throne — makes a token
6. Dawnhart Geist — gains you 2 life
7. Herald of the Pantheon — gains you 1 life
8. Kami of Transience — puts a +1/+1 counter on itself
9. Argothian Enchantress — draws you 1 card
10. Mesa Enchantress — draws you 1 card

255 other cards care about it too. These are the ones with the most connections.

a nontoken enchantment enters the battlefield — 3,691 cards in the game can cause this (Chains of Mephistopheles is one).

1. Historian's Boon — When Chains of Mephistopheles enters, Historian's Boon makes a token

an enchantment enters the battlefield — 3,743 cards in the game can cause this (Chains of Mephistopheles is one).

When Chains of Mephistopheles enters:

1. Calix, Guided by Fate — puts a counter on a creature
2. Elvish Archivist — draws you 1 card
3. Victor, Valgavoth's Seneschal — surveils
4. Strength from the Fallen — gives +X/+X, where X is the number of creature cards in your graveyard
5. Doomwake Giant — shrinks a creature by -1/-1
6. Cacophony Unleashed — turns something into a creature
7. Ghostly Dancers — makes a token
8. Thassa's Devourer — mills a card
9. Killian, Decisive Mentor — taps a creature
10. Thoughtrender Lamia — makes an opponent discard a card

62 other cards care about it too. These are the ones with the most connections.

a card is drawn — 3,815 cards in the game can cause this (Chains of Mephistopheles is one).

When Chains of Mephistopheles makes a player draw a card:

1. Teferi's Tutelage — mills a card
2. Temmet, Naktamun's Will — gives +1/+1
3. Niv-Mizzet, Parun — deals 1 damage
4. Aether Syphon — mills a card
5. Ob Nixilis, the Hate-Twisted — deals 1 damage
6. The Locust God — makes a token
7. Starving Revenant — makes each opponent lose 1 life
8. Diviner's Wand — gets +1/+1
9. Ominous Seas — puts a foreshadow counter on itself
10. Dream Trawler — gets +1/+0

57 other cards care about it too. These are the ones with the most connections.

a card in a graveyard — 7,589 cards in the game can cause this (Chains of Mephistopheles is one).

Chains of Mephistopheles:

1. Hedonist's Trove — puts cards into the graveyard that Hedonist's Trove can bring back
2. Samwise Gamgee — puts cards into the graveyard that Samwise Gamgee can bring back
3. Fire Nation Salvagers — puts cards into the graveyard that Fire Nation Salvagers can bring back
4. Bloodbond March — puts cards into the graveyard that Bloodbond March can bring back
5. Gale, Waterdeep Prodigy — puts cards into the graveyard that Gale, Waterdeep Prodigy can bring back
6. Harness the Storm — puts cards into the graveyard that Harness the Storm can bring back
7. Transplant Theorist — puts cards into the graveyard that Transplant Theorist can bring back
8. Heart-Shaped Herb — puts cards into the graveyard that Heart-Shaped Herb can bring back
9. Wayward Angel — fills your graveyard toward the 7 or more cards Wayward Angel needs
10. Sidequest: Card Collection // Magicked Card — fills your graveyard toward the 8 or more cards Sidequest: Card Collection // Magicked Card needs

434 other cards care about it too. These are the ones with the most connections.

anything goes to a graveyard — 7,589 cards in the game can cause this (Chains of Mephistopheles is one).

When a card hits the graveyard thanks to Chains of Mephistopheles:

1. The Haunt of Hightower — puts a +1/+1 counter on itself
2. Duskmantle Guildmage — makes each opponent lose 1 life
3. Vulturous Zombie — puts a +1/+1 counter on itself
4. Quest for Ancient Secrets — puts a quest counter on itself
5. Bloodchief Ascension — makes each opponent lose 2 life
6. Compost — draws you 1 card
7. Measure of Wickedness — gives an opponent control of itself
8. Energy Field — sacrifices itself

3 other cards care about it too. These are the ones with the most connections.