Ego Drain

a card is discarded — 2,042 cards in the game can cause this (Ego Drain is one).

When a permanent makes a player discard a card thanks to Ego Drain:

1. Sangromancer — gains you 3 life
2. Lo and Li, Royal Advisors — puts a counter on an Advisor
3. Nath of the Gilt-Leaf — makes a token
4. Tourach, Dread Cantor — puts a +1/+1 counter on itself
5. Tinybones, Pocket Nuisance — deals 1 damage
6. Tinybones, Bauble Burglar — hits a graveyard
7. Fell Specter — makes each opponent lose 2 life
8. Spirit Cairn — makes a token
9. Confessor — gains you 1 life
10. Hostile Investigator — triggers

51 other cards care about it too. These are the ones with the most connections.

anything is exiled — 2,497 cards in the game can cause this (Ego Drain is one).

1. The War Doctor — When a permanent is exiled thanks to Ego Drain, The War Doctor puts a time counter on itself

a sorcery is cast — 3,720 cards in the game can cause this (Ego Drain is one).

When Ego Drain is cast:

1. Spellweaver Volute — copies a spell
2. Lilah, Undefeated Slickshot — gets +1/+1
3. Niblis of Frost — gets +1/+1
4. Primeval Bounty — puts 3 counters on a creature
5. Tetsuko Umezawa, Pursuer — gets +1/+1
6. Thor, God of Thunder — deals that spell's mana value damage
7. Krile Baldesion — brings a card back
8. Summon: Good King Mog XII — makes a token
9. Kykar, Wind's Fury — makes a token
10. Blood Funnel — sacrifices a creature

424 other cards care about it too. These are the ones with the most connections.

a card in a graveyard — 7,589 cards in the game can cause this (Ego Drain is one).

1. Bloodbond March — Ego Drain puts cards into the graveyard that Bloodbond March can bring back
2. Heart-Shaped Herb — Ego Drain puts cards into the graveyard that Heart-Shaped Herb can bring back
3. Enlightened Confidant — Ego Drain puts cards into the graveyard that Enlightened Confidant can bring back
4. Tergrid, God of Fright // Tergrid's Lantern — Ego Drain puts cards into the graveyard that Tergrid, God of Fright // Tergrid's Lantern can bring back
5. Grazing Kelpie — Ego Drain puts cards into the graveyard that Grazing Kelpie can bring back
6. Dauthi Voidwalker — Cards Ego Drain would put into an opponent's graveyard are exiled by Dauthi Voidwalker instead, and it can play from among them
7. Endurance — Ego Drain puts cards into the graveyard that Endurance can bring back
8. Thieves' Guild Enforcer — Ego Drain fills an opponent's graveyard toward the 8 or more cards Thieves' Guild Enforcer needs
9. Soaring Thought-Thief — Ego Drain fills an opponent's graveyard toward the 8 or more cards Soaring Thought-Thief needs
10. Merfolk Windrobber — Ego Drain fills an opponent's graveyard toward the 8 or more cards Merfolk Windrobber needs

434 other cards care about it too. These are the ones with the most connections.

anything goes to a graveyard — 7,589 cards in the game can cause this (Ego Drain is one).

When a card hits the graveyard thanks to Ego Drain:

1. The Haunt of Hightower — puts a +1/+1 counter on itself
2. Duskmantle Guildmage — makes each opponent lose 1 life
3. Vulturous Zombie — puts a +1/+1 counter on itself
4. Bloodchief Ascension — makes each opponent lose 2 life
5. Compost — draws you 1 card
6. Planar Void — hits a graveyard

5 other cards care about it too. These are the ones with the most connections.

anything is cast — 31,128 cards in the game can cause this (Ego Drain is one).

When Ego Drain is cast:

1. Windrider Wizard — draws you 1 card
2. Relic Amulet — puts a charge counter on itself
3. Rockslide Sorcerer — deals 1 damage
4. Umara Wizard // Umara Skyfalls — grants flying
5. Alania, Divergent Storm — makes an opponent draw 1 card
6. Umara Mystic — gets +2/+0
7. Master of Winds — triggers

5 other cards care about it too. These are the ones with the most connections.